Hidradenitis Suppurativa · United Kingdom

AI representation changes with the question.

Four AI systems answered 1,143 questions about hidradenitis suppurativa, asked in English from a UK dermatologist's perspective and spread across five areas of the treatment conversation. Which treatments they name depends on the area.

Illustration of AI representation of hidradenitis suppurativa treatments in the United Kingdom: a skin cross-section linked to question-area panels.

Adalimumab is the most often named molecule overall, in 89% of all answers. In answers about emerging therapies it is named in 50% — and bimekizumab in 86%.

stakeholder
Dermatologists
language
English
questions
1,143
responses
4,572
AI systems
4
question areas
5
measured
September 2026

01 · AI Representation Map

Different questions, different representation.

The overall figure counts every question together. Split the same answers by what was asked, and a molecule named in most answers about one area can be almost absent from another.

AI Visibility % by question area

% of answers that name the molecule at least once. Select a question area to see how often each molecule is named in answers about it.

N = 4,572 responses from four AI systems · each area's base is shown with it

AI Visibility % by question area. % of answers that name the molecule at least once. Select a question area to see how often each molecule is named in answers about it. N = 4,572 responses from four AI systems · each area's base is shown with it.
All questionsn = 4,572Efficacyn = 1,704Safety & tolerabilityn = 1,152Conveniencen = 960Treatment adherencen = 180Emerging therapiesn = 576
Named across the conversationIn at least half of the answers in every question area.
Adalimumab89%98%90%95%97%50%
Secukinumab81%90%76%80%75%72%
Bimekizumab76%87%67%65%53%86%
Named in some areas more than othersBelow half in at least one area, and named mostly outside emerging-therapy questions.
Clindamycin39%42%42%54%33%<1%
Infliximab34%43%29%38%44%2%
Rifampicin21%23%27%25%23%0%
Doxycycline13%7%12%33%4%0%
Ertapenem8%10%6%12%2%<1%
Minocycline7%3%6%21%2%0%
Acitretin6%4%7%10%6%0%
Spironolactone6%5%3%13%2%<1%
Anakinra5%8%4%1%1%5%
Tetracycline*4%2%4%10%3%<1%
Dapsone4%2%5%8%3%0%
Metformin3%2%3%6%1%<1%
Colchicine<1%<1%1%<1%0%0%
Named mostly about emerging therapiesMost of the answers that name it are answers to emerging-therapy questions.
Povorcitinib13%7%4%2%2%73%
Sonelokimab11%6%3%0%3%61%
Upadacitinib10%6%3%2%3%50%
Lutikizumab9%5%2%0%2%53%
Spesolimab8%3%2%<1%0%50%
Remibrutinib5%<1%<1%0%0%40%
Izokibep2%1%<1%<1%0%15%
Brivekimig1%<1%0%0%0%9%
Tibulizumab<1%0%0%0%0%7%
Abdakibart<1%<1%<1%<1%0%3%
Tulisokibart<1%0%<1%0%0%<1%
Zasocitinib<1%0%<1%0%0%<1%

* Includes answers that refer to tetracyclines as a class.

02 · The overall ranking

Three molecules are named in most answers. The overall ranking hides where representation changes.

Adalimumab, secukinumab and bimekizumab are each named in at least 76% of all answers; the next, clindamycin, in 39%. Share of Voice counts mentions rather than answers, so it also reflects how often a molecule is named within the answers that include it.

RankMoleculeAI Visibilityanswers naming itShare of Voiceof all molecule mentions
1Adalimumab89.2%4,059 / 4,54926.6%10,442 mentions
2Secukinumab81.3%3,708 / 4,56219.1%7,511 mentions
3Bimekizumab76.0%3,459 / 4,55320.0%7,868 mentions
4Clindamycin38.7%1,766 / 4,5666.2%2,454 mentions
5Infliximab33.6%1,532 / 4,5666.4%2,496 mentions
6Rifampicin21.4%977 / 4,5693.3%1,301 mentions
7Povorcitinib13.4%611 / 4,5712.3%915 mentions
8Doxycycline12.5%573 / 4,5702.0%793 mentions
9Sonelokimab10.6%484 / 4,5712.0%792 mentions
10Upadacitinib9.5%435 / 4,5711.5%581 mentions
11Lutikizumab9.3%425 / 4,5721.4%565 mentions
12Ertapenem8.1%369 / 4,5721.2%491 mentions
13Spesolimab7.7%353 / 4,5721.2%476 mentions
14Minocycline7.1%324 / 4,5721.2%452 mentions
15Acitretin5.8%266 / 4,5720.9%350 mentions
16Spironolactone5.7%261 / 4,5720.8%308 mentions
17Remibrutinib5.4%246 / 4,5720.8%318 mentions
18Anakinra5.1%233 / 4,5720.7%264 mentions
19Tetracycline3.8%176 / 4,5720.5%205 mentions
20Dapsone3.8%172 / 4,5710.6%226 mentions
21Metformin2.7%123 / 4,5710.4%151 mentions
22Izokibep2.4%110 / 4,5720.4%145 mentions
23Brivekimig1.3%58 / 4,5720.2%77 mentions
24Tibulizumab0.9%39 / 4,5720.1%45 mentions
25Abdakibart0.6%27 / 4,5720.1%32 mentions
26Colchicine0.4%17 / 4,5710.1%27 mentions
27Tulisokibart0.1%4 / 4,5720.0%4 mentions
27Zasocitinib0.1%4 / 4,5720.0%4 mentions

Secukinumab is named in more answers than bimekizumab (81.3% against 76.0%); bimekizumab has the larger Share of Voice (20.0% against 19.1%), with 2.27 mentions per answer that names it against 2.03. Reach and depth are different measures. Neither is a preference.

03 · Where representation changes

The same molecules, a different picture.

When the question is about emerging therapies

Adalimumab is the most often named molecule overall. In answers about emerging therapies it is named in 50% and moves to position 6; bimekizumab is named in 86%, and povorcitinib — 13% overall — in 73%.

  • All questions
  • Emerging-therapy questions
  1. Bimekizumab76% → 86%#3 → #1
  2. Povorcitinib13% → 73%#7 → #2
  3. Secukinumab81% → 72%#2 → #3
  4. Sonelokimab11% → 61%#9 → #4
  5. Lutikizumab9% → 53%#11 → #5
  6. Adalimumab89% → 50%#1 → #6
  7. Upadacitinib10% → 50%#10 → #7
  8. Spesolimab8% → 50%#13 → #8
  9. Remibrutinib5% → 40%#17 → #9
  10. Infliximab34% → 2%#5 → #15
  11. Clindamycin39% → <1%#4 → #19

Position is the order of molecules by how often they are named — a frequency, not a preference or a recommendation. Shown: every molecule named in at least a quarter of answers, overall or about emerging therapies (576 answers).

Similar reach overall, different profiles by area

Named at almost the same rate in answers about efficacy, the two separate elsewhere: secukinumab is named more often in answers about convenience and treatment adherence (the smallest area, 180 answers), bimekizumab in answers about emerging therapies.

  • Secukinumab
  • Bimekizumab
  1. All questions81% · 76%
  2. Efficacy90% · 87%
  3. Safety & tolerability76% · 67%
  4. Convenience80% · 65%
  5. Treatment adherence75% · 53%
  6. Emerging therapies72% · 86%

An overall figure averages over whatever was asked. Which part of the conversation matters is a question for each brand.

04 · Different AI systems, different treatment landscapes

The AI system being asked changes the treatment landscape.

Outside the questions about emerging therapies, Perplexity and Gemini name at least one tracked antibiotic in most of their answers; Claude and ChatGPT in about one in five.

Answers naming at least one tracked antibiotic, outside emerging-therapy questions
  1. Claude18%184 of 998 answers
  2. ChatGPT22%220 of 999 answers
  3. Gemini70%700 of 999 answers
  4. Perplexity78%783 of 999 answers

Tracked antibiotics: clindamycin, doxycycline, ertapenem, minocycline, rifampicin and tetracycline. The 576 answers about emerging therapies are left out, because those questions concern therapies in development.

Each tracked antibiotic, by AI system — all questions

  • Claude
  • ChatGPT
  • Perplexity
  • Gemini
  1. Clindamycin15–63%
  2. Rifampicin2–51%
  3. Doxycycline3–25%
  4. Ertapenem1–20%
  5. Minocycline2–19%
  6. Tetracycline1–10%

Rifampicin is named in 1.7% of ChatGPT's answers and 51.5% of Gemini's. Tetracycline includes answers that refer to tetracyclines as a class.

Different systems can represent the same treatment landscape very differently. Visibility shows the difference; it does not show which system is right.

Beyond Visibility

Visibility tells you where you are named. AI Representation tells you what is said when you are.

This benchmark shows which molecules AI names, and how that changes with the question and with the system asked. Being named is a hygiene factor, not a differentiator. What matters is how AI models describe your products when they are named — and whether that description aligns with your business objectives and strategic priorities.

This is where Theralexis comes in. Our experts are experienced pharma commercial leaders who help pharma marketing and omnichannel teams identify and focus on the biggest commercial opportunities. We use an AI Representation assessment as the starting point, then provide channel and content recommendations to strengthen how your products are represented across AI.

Full assessment

What a full assessment adds

Example: Your brandUnited Kingdom · Dermatologists

  • Competitive positioning

    Your brand vs competitorsYour brandCompetitor ACompetitor BCompetitor C
  • Product attributes

    EfficacySafetyDosingOutcomesYour brandCompetitor ACompetitor B
  • Strategic alignment

    Intended vs describedIntended positioningPriority messageDifferentiationTarget role
  • Source intelligence

    Sources shaping the answerGuidelinesPublicationsPharma-ownedHCP / professional
  • Content recommendations

    Approved claimsEvidenceExisting contentOpportunities

This benchmark measured which molecules AI names. A full assessment adds what it does not — how AI describes your brand, which sources shape that, and what to do about it — for your brand, indication, market and launch situation.

Your market

See how AI represents your therapy in the questions that matter to your brand.

A public benchmark shows one market, one audience and one moment. We measure the same for your brand, indication, geography and launch situation — which systems name it, in which parts of the conversation, and how they describe it.

About this benchmark

What was measured

Four AI systems — Claude, ChatGPT, Gemini and Perplexity, each with web access — answered the same questions about hidradenitis suppurativa and its systemic treatment, asked in English from the perspective of a dermatologist in the United Kingdom. Each system answered each question once, in September 2026.

Every question belongs to one of five question areas — efficacy, safety and tolerability, convenience, treatment adherence and emerging therapies — and, within its area, to one topic. The areas are not the same size, so every figure on this page is stated against its own base.

AI Visibility is the percentage of answers in scope that name a molecule at least once: all questions, one question area or one AI system. It records that a molecule was named. It does not show how the molecule was described, whether it was recommended, or whether the answer was accurate.

Share of Voice is a molecule's share of all molecule mentions, counting every mention, including repeats within one answer. It is a different measure from AI Visibility, and it is reported across all questions and all AI systems together only.

Position is the order of molecules by AI Visibility within a scope. It says how often a molecule is named, and nothing more.

Each molecule's base is the answers in which it was assessed. For fewer than 1 in 100 answers per molecule, a molecule could not be assessed; those answers are left out of its base rather than counted as not naming it.

Tetracycline is also counted where an answer refers to tetracyclines as a class, so its figures are less specific than other molecules'; they are marked wherever they appear.

What was not measured

This is a Visibility benchmark. It measures which molecules AI systems name, and how often, in which parts of the treatment conversation. It does not show how those systems describe a therapy, whether it is described accurately, which attributes it is associated with, or which sources shaped the answer. Brand names were rarely used in these answers and are not reported here.

A product with high AI Visibility might still be working against your commercial objectives. That's why AI Visibility is not necessarily a competitive differentiator. When AI talks about your brand, you need to understand what is said.

This is why a full Theralexis assessment goes much further — beyond AI Visibility metrics provided by generic SEO and GEO tools. We reveal how AI models talk about your product, how that aligns with your strategic priorities, the sources and channels shaping it, and what actions can strengthen your competitive position.

Market
Hidradenitis Suppurativa · United Kingdom
Stakeholder
Dermatologists
Language
English
Questions
1,143
Responses
4,572
Question areas
Efficacy
Safety & tolerability
Convenience
Treatment adherence
Emerging therapies
Measured
September 2026
Tracked
28 molecules
AI systems measured
ChatGPT, Claude, Gemini, Perplexity

Full benchmark

Explore the full benchmark.

This public benchmark shows how AI Visibility changes across the HS treatment conversation. Theralexis goes deeper — revealing how competing treatments are represented across questions and AI systems, and where the competitive picture changes.