Methodology

A structured approach to AI Representation Intelligence

Theralexis combines advanced AI systems, deep medical context and real-world evidence to reveal how your brand is represented — and what it means for your strategy.

Three principles are set apart from the diagram: Strategic by design — we tailor the scope to your brand, markets, therapeutic area and priorities; Evidence-grounded — our analysis is based on trusted sources and scientific principles; Actionable by nature — clear insights that drive better decisions. Beside them, a single diagram of the Theralexis assessment environment. On the left, under the heading AI Systems, a column of cards names the AI systems assessed: ChatGPT, Claude, Gemini, Perplexity, Microsoft Copilot, and more. At the centre, the Theralexis mark on a lit node captioned AI Representation Intelligence. On the right, under the heading HCPs and personas, a column of cards names the healthcare perspectives modelled, each with a portrait: Cardiologist, evidence explorer; GP or internist, treatment decision maker; Pharmacist, therapy advisor; Payer or HTA, value assessor; Researcher, scientific investigator; and more. Fine luminous filaments connect the AI systems to the centre, the centre to the personas, and cascade downward onto a wide layered glass platform labelled Evidence and context, which carries six categories: Scientific literature, Clinical guidelines, Regulatory information, Medical education, Real-world evidence, and News and conferences. A panel at the lower right lists the strategic outcomes: benchmark versus competitors, identify gaps and risks, discover opportunities, track change over time, and drive strategic action.

Our methodology

From complexity to clarity.

A repeatable process that turns AI outputs into structured intelligence you can act on.

  1. 01

    Define

    Define the strategic scope that matters most for your brand and markets.

  2. 02

    Capture

    Collect AI-generated responses across selected systems, personas and languages.

  3. 03

    Evaluate

    Assess outputs using our proprietary frameworks and expert analysis.

  4. 04

    Compare

    Benchmark against competitors and category leaders.

  5. 05

    Interpret

    Translate findings into clear strategic implications.

  6. 06

    Track

    Monitor representation over time and measure progress, where the engagement is ongoing.

Why you can trust our findings

Reliable intelligence about AI representation takes more than collecting answers. AI systems differ from one another, from market to market and over time, and that variation is not noise to be removed — it is part of what Theralexis measures. Theralexis measures and interprets how AI systems represent your brand; it does not control, guarantee or manipulate what they say.

  • Reality AI systems answer the same question differently, and the same system can answer differently twice.

    Our approach Theralexis uses an assessment methodology inspired by scientific research principles. Responses are collected repeatedly, variability is measured and every AI system is assessed under consistent conditions. This provides a robust foundation for understanding how your brand is represented across AI systems.

  • Reality It matters who asks the question. A cardiologist from Germany can get a different answer than an endocrinologist from Spain.

    Our approach Together with our clients, we create realistic stakeholder personas that resemble the audiences they actually engage with. Every AI system is then assessed using these personas so results can be compared across stakeholders, markets and audiences.

  • Reality AI systems evolve, and how they represent a brand may change.

    Our approach Where an engagement is ongoing, assessments can be repeated over time. Historical findings are retained, allowing changes after AI system updates to be benchmarked and analysed.

  • Reality Representation is local: answers differ from one country and language to the next.

    Our approach Each market and language can be individually assessed and compared. Local differences then show in the findings rather than averaging out across regions.

  • Reality Citations show which sources an answer is based on — not how accurate the answer actually is.

    Our approach Sources are captured and shared with our clients. Therapeutic Accuracy assesses whether scientific evidence is represented accurately.

Every assessment is designed together with our clients. The questions, stakeholders, therapeutic areas, markets and languages are selected to match the decisions that matter most to them. The result is intelligence grounded in their own market, their own brand and their strategic priorities — not a generic AI benchmark.

Start a conversation

Explore how Theralexis could assess a specific brand, therapy, market or strategic question.